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B-type Natriuretic Peptide (BNP) is a hormone released by your heart's ventricles in response to increased wall stretching from volume or pressure overload. It is the primary blood marker for diagnosing and monitoring heart failure severity. A low BNP effectively rules out heart failure in breathless patients with a negative predictive value exceeding 95%.
Also known as: B-type Natriuretic Peptide, BNP, Brain Natriuretic Peptide, 利钠肽.B
High BNP confirms ventricular wall stress and strongly suggests heart failure. Low BNP effectively rules out heart failure in breathless patients with a negative predictive value exceeding 95%.
Standard diagnostic cutoff is above 100 pg/mL. Optimal is below 50 pg/mL. BNP naturally increases with age and is higher in women.