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Albumin is the most abundant protein in the blood, produced continuously by the liver, and serves as the body's primary transport vehicle for hormones, nutrients, fatty acids, and drugs. Low albumin is one of the most reliable markers of chronic liver disease, malnutrition, or systemic illness — reflecting the liver's inability to maintain protein synthesis under stress. It also affects the interpretation of other results: calcium and certain medications are partially bound to albumin, so their effective levels change when albumin is low.
Also known as: Alb, Albumin, Albumin (Plasma), Albumin (Serum), Albumin, Serum, Serum Albumin
High albumin typically reflects dehydration. Low albumin signals chronic liver disease, kidney disease, malnutrition, or chronic inflammation. Persistently low albumin is one of the strongest predictors of mortality.
Standard flag is below 3.5 g/dL. Functional practitioners target 4.2-5.0 g/dL. Albumin below 4.0, even when technically normal, correlates with increased mortality.