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Growth hormone (GH) is produced by the anterior pituitary in pulsatile bursts, primarily during deep sleep and high-intensity exercise. It drives tissue repair, fat mobilization, muscle protein synthesis, and bone remodeling. Because GH is pulsatile and a random blood draw is nearly meaningless, IGF-1 is used as the stable steady-state surrogate for GH status.
Also known as: GH, Growth Hormone, HGH, Human Growth Hormone, Somatotropin, 生长激素
High GH causes acromegaly from a pituitary adenoma. Low GH in adults causes increased visceral fat, decreased lean mass, and reduced bone density.
Random GH levels are nearly useless due to pulsatile secretion. IGF-1 is used as the steady-state surrogate for GH status.