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Lactate dehydrogenase (LDH) is an enzyme present in nearly every cell in your body, released when tissue damage or excessive cell turnover occurs. It serves as a nonspecific but sensitive marker of cellular injury, from hemolytic anemia and liver disease to lymphoma. LDH trending upward in a known cancer patient signals disease progression before imaging changes appear.
Also known as: L.D.H, Lactate Dehydrogenase, Lactic Dehydrogenase, LD, LDH, LDH (Lactic Dehydrogenase), LDH-Lactic Dehydrogenase
High LDH indicates active tissue destruction from hemolytic anemia, lymphoma, liver damage, pulmonary embolism, or myocardial infarction. Low LDH is rare and generally not significant.
Standard range is 120-246 U/L. Functional practitioners target 140-200 U/L. LDH trending upward in cancer patients signals disease progression.