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The BUN-to-creatinine ratio is a quick tool for distinguishing different causes of elevated kidney markers. A high ratio (above 20) with elevated BUN suggests dehydration, high protein intake, or upper gastrointestinal bleeding — a 'pre-renal' cause where kidney function itself may be intact. A ratio below 10 with elevated creatinine points toward intrinsic kidney disease or low protein intake. The ratio is normal (10–20) in most people with stable, mild chronic kidney disease.
Also known as: Azote uréique/créatinine, Azoto ureico/Creatinina, BUN:Cr Ratio, BUN/Creat, BUN/Creatinine, BUN/Creatinine Ratio, Nitrógeno ureico/Creatinina, Üre azotu/Kreatinin
A high ratio above 20:1 suggests dehydration, heart failure, or GI bleeding. A low ratio below 10:1 points to intrinsic kidney damage or liver disease.
Standard range is 10:1 to 20:1. Functional practitioners target 12:1-16:1.