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Complement C3 is the most abundant complement protein and a central hub of your innate immune system. Low C3 indicates active complement consumption from immune complex diseases like lupus nephritis. Elevated C3 behaves as an acute-phase reactant, rising with inflammation and metabolic syndrome.
Also known as: C3, C3 Complement, Complement C3, Complément C3, Complemento C3, 보체C3, 补体 C3, 补体C3
High C3 is associated with chronic inflammation, insulin resistance, and cardiovascular risk. Low C3 results from complement consumption in active lupus, severe infections, or hereditary deficiencies.
Standard range is 90-180 mg/dL. Optimal is 100-150 mg/dL. Elevated C3 within range correlates with metabolic syndrome.