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D-Dimer is a fibrin degradation product released when your body breaks down blood clots. It serves as a sensitive marker for active clot formation and dissolution. Elevated levels may indicate deep vein thrombosis, pulmonary embolism, or other conditions where both clotting and fibrinolysis are activated.
Also known as: D Dimer, D-dimer, D-Dimère, D-Dímero, D-다이머, D-二聚体, DDimer, Fibrin D-dimer
High D-Dimer indicates active clot breakdown from DVT, PE, DIC, surgery, or infection. A normal D-Dimer effectively rules out DVT and PE in patients with low-to-intermediate pre-test clinical probability.
Standard cutoff is below 0.50 mg/L. D-Dimer increases with age - age-adjusted cutoffs improve specificity.