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CEA (Carcinoembryonic Antigen) is a protein normally near-absent in healthy adults. It is primarily used to monitor colorectal cancer treatment response and detect recurrence — rising CEA after surgery often signals metastatic disease before imaging can detect it. Non-malignant causes include heavy smoking, cirrhosis, and ulcerative colitis.
Also known as: Carcinoembryonic Antigen, CEA, CEA Total, 癌胚 抗原
High CEA is most significant during post-surgical colorectal cancer monitoring. Non-malignant causes include heavy smoking, cirrhosis, and ulcerative colitis. Low CEA is normal.
Standard cutoff is below 3.0 ng/mL for nonsmokers. Optimal is below 2.0 ng/mL. CEA should never be used alone for cancer screening.